产品货号:
Z17069
中文名称:
GFRA2抗体
英文名称:
Anti-GFRA2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-GFRA2 Antibody |
| 指标别名 | GDNF family receptor alpha 2;GDNF receptor alpha 2;GDNF receptor beta;GDNFR alpha 2;GDNFR beta;GDNFRB;GFR alpha 2;GFRA2;Neurturin receptor alpha;NRTNR ALPHA;NTNR alpha;NTNRA;RET ligand 2;RETL2;TRNR2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | GFRA2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | GFR alpha 2 antibody was raised against a 15 amino acid peptide near the center of human GFR alpha 2.The immunogen is located within amino acids 360 - 410 of GFR alpha 2. |
| 计算分子量 | 52kDa |
| 成分 | GFR alpha 2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | GFR alpha 2 Antibody is Ion exchange chromatography purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | Members of the glial cell line-derived neurotrophic factor (GDNF) family,including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation.Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha,which is a cell surface receptor for NTN.The cDNAs encoding NTNRalpha from human,rat,chicken,and mouse have been cloned recently.NTNRalpha was also termed GDNFR汕,Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFR汐-2 recently.GFR汐-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF.Thus,NTN,GFR汐-2,and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function. |
| Uniprot ID | O00451 |
| 基因名全称 | GDNF family receptor alpha 2 |
| 蛋白名全称 | GDNF family receptor alpha 2 |
| 推荐稀释比 | GFR alpha 2 antibody can be used for detection of GFR alpha 2 by Western blot at 1μg/mL.A 52kDa band should be detected.Antibody can also be used for immunocytochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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